The secretion of urine by dehydrated and normal infants.

High blood ureas have been found in untreated cases (Schloss, 1918; Bessau, Rosenbaum and Leichtentritt, 1922; Cohen, Miller and Kramer, 1933), and Schloss considered that haemoconcentration was not enough to account for this finding. By means of the phenolsulphonphthalein test and Ambard's coefficient of urea excretion he showed that the function of the kidney was impaired in a group of infants recovering from gastroenteritis. Schoenthal, Lurie and Kelly (1933) came to the same conclusion after examining the urea clearances of a few babies who were dehydrated. The controls in both these investigations were normal infants whose urine volumes were usually much higher than those of the sick infants.